Chemiluminescent materials have been the subject of extensive research in the field of analytical chemistry due to their high sensitivity, high luminescence efficiency and simple instrumentation. Among these, luminol and derivatives that contain a pyridazine unit are the most attractive CL compoundsand they have been used both in the analysis of food, pesticide, air pollution, biologically active compounds (e.g. glucose, adenine, folic acid, lactic acid, dopamine, glycolic acid), immunoassay and DNA probe assays. Additionally, they can be employed in forensic applications due to their high sensitivity towards blood. In spite of these widespread applications, it has not yet been possible to develop CL luminol and/or pyridazine based polymers as sensors, since solubility problems, limited thickness of the polymer film and the complex polymerization mechanism of luminol constrain their use.
Recently, we have initiated a program aimed at the design and synthesis of novel CL materials that can easily be polymerized without the destruction of the CL unit during the polymerization process
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http://pubs.rsc.org/en/Content/ArticleLanding/2009/CC/b814258k#!divAbstract
http://onlinelibrary.wiley.com/doi/10.1002/elan.201000141/abstract
A glow in the dark! SNS-Lum comes into contact with blood!