Comparative and Evolutionary Biology Group
METU Department of Biological Sciences, Ankara, Turkey
Our team studies human evolution at the transcriptome and genomic levels. Our previous work focused on differences in gene expression timing in brain development between humans and chimpanzees that may underlie cognitive differences between these species. Our group continues working on genomic and transcriptomic variation in humans and primates.
We are also interested in brain aging. Specifically, we aim to understand the causes and regulation of molecular changes that occur during brain aging, some of which may be driving age-related cognitive decline. Our current work focuses on the roles of deleterious genetic load, diet and caloric restriction, and chronic stress as factors in brain aging.
We use rodent and primate models, transcriptomics and meta-analysis of published data to investigate these questions.